Coevolution at the proteome scale - Institute for Protein Design
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Coevolution at the proteome scale - Institute for Protein Design
Today we report in Science the identification of hundreds of previously uncharacterized protein–protein interactions in E. coli and the pathogenic bacterium M. tuberculosis. These include both previously unknown protein complexes and previously uncharacterized components of known complexes. This research was led by postdoctoral fellow Qian Cong and included former Baker lab graduate student Sergey Ovchinnikov, now a John Harvard Distinguished Science
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Big Data Shapes the Fold for of Hundreds of Protein Families - Institute for Protein Design
Learning Epistasis and Residue Coevolution Patterns: Current Trends and Future Perspectives for Advancing Enzyme Engineering
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Improved protein structure prediction using predicted interresidue orientations
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Co-evolutionary landscape at the interface and non-interface regions of protein-protein interaction complexes - ScienceDirect
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Computed structures of core eukaryotic protein complexes
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PDF) Large-scale discovery of protein interactions at residue resolution using co-evolution calculated from genomic sequences
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Deploying synthetic coevolution and machine learning to engineer protein- protein interactions
![Coevolution at the proteome scale - Institute for Protein Design](https://www.nejm.org/na101/home/literatum/publisher/mms/journals/content/nejm/2021/nejm_2021.385.issue-23/nejmcibr2113027/20211129/images/img_medium/nejmcibr2113027_f1.jpeg)
Predicting Proteome-Scale Protein Structure with Artificial Intelligence
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Computed structures of core eukaryotic protein complexes
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July, 2019 - Institute for Protein Design
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Co-evolution of interacting proteins through non-contacting and non-specific mutations
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News - Institute for Protein Design